Raises the defense of one party member until the end of the battle.
| Price | |
| Buy | 1000 DP |
| Sell | 500 DP |
| Target |
| Party |
| Chapter 1 | Chapter 2 | Chapter 3 | Chapter 4 | Chapter 5 | Chapter 7 | Chapter 8 |
| X | X |
Defense Spray is: found in the field, available at shops.
| Shop | Location |
| Chemist | Chimera Lab |
| Mole Cricket Shop | Empire Porky Building |